The Joel and Ellie editions are the same thing anyway just with a different picture on the canvas wrap, open one keep the other sealed.
I like to keep my stuff sealed if possible, but if it's the only copy of the game I'm ever going to buy I'll open it, I'm not buying a game then never playing it.
If you're looking to maximise the value then of course sealed is the way to go, but it's very hit and miss when trying to guess what will become valuable in the future. Take the Liara T'Soni bishojou statue for example, I had two sealed copies and sold them both for peanuts, now they are selling for upto four times the original price
